Reactome | glutamate + acetyl CoA => N-acetyl glutamate + CoA

Schema > Reaction > Entries

glutamate + acetyl CoA => N-acetyl glutamate + CoA Show undefined attributes

catalystActivity	[CatalystActivity:9865853] acetyl-CoA:L-glutamate N-acetyltransferase activity of NAGS(19-534) [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9865855
displayName	glutamate + acetyl CoA => N-acetyl glutamate + CoA
eventOf	[Pathway:R-MMU-70635] Urea cycle - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] - Mus musculus
inferredFrom	[Reaction:R-HSA-70542] glutamate + acetyl CoA => N-acetyl glutamate + CoA - Homo sapiens
input	[SimpleEntity:R-ALL-113559] Ac-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-113552] L-Glu [mitochondrial matrix]
isInDisease	false
isInferred	true
name	glutamate + acetyl CoA => N-acetyl glutamate + CoA
output	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-30471] NAcGlu [mitochondrial matrix]
regulatedBy	[PositiveRegulation:R-HSA-70543] Positive regulation by 'L-Arg [mitochondrial matrix]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-70542
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-70635] Urea cycle
(precedingEvent)	[Reaction:R-MMU-70555] 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]
(inferredTo)	[Reaction:R-HSA-70542] glutamate + acetyl CoA => N-acetyl glutamate + CoA