Reactome | COPI-dependent Golgi-to-ER retrograde traffic

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COPI-dependent Golgi-to-ER retrograde traffic Show undefined attributes

created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9978632
displayName	COPI-dependent Golgi-to-ER retrograde traffic
eventOf	[Pathway:R-MMU-8856688] Golgi-to-ER retrograde transport - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22584] retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-6811415] RAB:GTP recruits GBF1 to the Golgi membrane - Mus musculus [Reaction:R-MMU-6811411] GBF1 recruits ARF:GDP to the Golgi - Mus musculus [Reaction:R-MMU-6811414] GBF1 stimulates nucleotide exchange on ARF - Mus musculus [Reaction:R-MMU-6811412] Active ARF recruits coatomer to the Golgi - Mus musculus [Reaction:R-MMU-6811417] ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi - Mus musculus [Reaction:R-MMU-6811418] ARFGAPs stimulate ARF GTPase activity at the Golgi membrane - Mus musculus [Reaction:R-MMU-6811426] Retrograde COPI vesicles bind kinesin and microtubules - Mus musculus [Reaction:R-MMU-6811423] Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs - Mus musculus [BlackBoxEvent:R-MMU-6811427] COPI vesicle uncoating at the ER - Mus musculus [Reaction:R-MMU-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Mus musculus [Reaction:R-MMU-6811422] NSF ATPase activity dissociates cis-SNARE at the ER - Mus musculus
inferredFrom	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Homo sapiens
isInDisease	false
isInferred	true
name	COPI-dependent Golgi-to-ER retrograde traffic
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-6811434
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8856688] Golgi-to-ER retrograde transport
(inferredTo)	[Pathway:R-HSA-6811434] COPI-dependent Golgi-to-ER retrograde traffic

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