Reactome | RHO GTPases Activate WASPs and WAVEs

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RHO GTPases Activate WASPs and WAVEs Show undefined attributes

created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9978074
displayName	RHO GTPases Activate WASPs and WAVEs
eventOf	[Pathway:R-MMU-195258] RHO GTPase Effectors - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-2197698] Src phosphorylate WASP,N-WASP - Mus musculus [Reaction:R-MMU-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) - Mus musculus [Reaction:R-MMU-2130194] ABL phosphorylates WAVEs - Mus musculus [Reaction:R-MMU-2029469] p-ERK phosphorylates WAVEs and ABI - Mus musculus [Reaction:R-MMU-2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - Mus musculus [Reaction:R-MMU-2197690] Detachment of WASP/WAVE - Mus musculus [BlackBoxEvent:R-MMU-2029473] Branching and elongation of mother and daughter filaments - Mus musculus
inferredFrom	[Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs - Homo sapiens
isInDisease	false
isInferred	true
name	RHO GTPases Activate WASPs and WAVEs
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5663213
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-195258] RHO GTPase Effectors
(hasEncapsulatedEvent)	[Pathway:R-MMU-8848021] Signaling by PTK6 [Pathway:R-MMU-9006115] Signaling by NTRK2 (TRKB)
(inferredTo)	[Pathway:R-HSA-5663213] RHO GTPases Activate WASPs and WAVEs

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