Reactome | Translocation of Vav1 to CD28

Schema > Reaction > Entries

Translocation of Vav1 to CD28 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9892336
displayName	Translocation of Vav1 to CD28
eventOf	[Pathway:R-MMU-389359] CD28 dependent Vav1 pathway - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-389354] Activation of Vav1 - Mus musculus
inferredFrom	[Reaction:R-HSA-389352] Translocation of Vav1 to CD28 - Homo sapiens
input	[Complex:R-MMU-388786] CD28:Grb2 [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-434625] Vav1 [cytosol]
isInDisease	false
isInferred	true
name	Translocation of Vav1 to CD28
output	[Complex:R-MMU-389334] VAV1:PIP3:CD28:GRB2 [plasma membrane]
precedingEvent	[Reaction:R-MMU-388814] Grb2 binds CD28 - Mus musculus [Reaction:R-MMU-389158] CD28 bound PI3K phosphorylates PIP2 to PIP3 - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-389352
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-389359] CD28 dependent Vav1 pathway
(precedingEvent)	[Reaction:R-MMU-389354] Activation of Vav1
(inferredTo)	[Reaction:R-HSA-389352] Translocation of Vav1 to CD28