Reactome | Glce epimerises GlcA to IdoA

Schema > Reaction > Entries

authored	[InstanceEdit:2024092] Jassal, B, 2011-12-14
catalystActivity	[CatalystActivity:2024105] UDP-glucuronate 5'-epimerase activity of Glce [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:2024092] Jassal, B, 2011-12-14
dbId	2024090
displayName	Glce epimerises GlcA to IdoA
edited	[InstanceEdit:2024092] Jassal, B, 2011-12-14
input	[DefinedSet:R-MMU-2161427] HS(1)-PGs [Golgi lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2024112] Characterization of the D-glucuronyl C5-epimerase involved in the biosynthesis of heparin and heparan sulfate [LiteratureReference:2024103] Cloning, Golgi localization, and enzyme activity of the full-length heparin/heparan sulfate-glucuronic acid C5-epimerase
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Glce epimerises GlcA to IdoA
orthologousEvent	[Reaction:R-HSA-2076371] GLCE epimerises more GlcA to IdoA as sulfate content rises - Homo sapiens [Reaction:R-HSA-2024100] GLCE epimerises GlcA to IdoA - Homo sapiens
output	[DefinedSet:R-MMU-2161463] HS(2)-PGs [Golgi lumen]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2024090
summation	[Summation:2024115] The enzyme glucuronyl C5-epimerase (Glce) mediates the epime...

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