Reactome | Removal of remaining Flap from the C-strand

Schema > Reaction > Entries

Removal of remaining Flap from the C-strand Show undefined attributes

catalystActivity	[CatalystActivity:9865138] 5'-flap endonuclease activity of FEN1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9878145
displayName	Removal of remaining Flap from the C-strand
eventOf	[Pathway:R-MMU-174437] Removal of the Flap Intermediate from the C-strand - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-174456] Joining of adjacent Okazaki fragments of the C-strand - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
inferredFrom	[Reaction:R-HSA-174446] Removal of remaining Flap from the C-strand - Homo sapiens
input	[Complex:R-MMU-174440] Processive complex loaded on telomere:Okazaki fragments:Remaining Flap [nucleoplasm]
isInDisease	false
isInferred	true
name	Removal of remaining Flap from the C-strand
output	[Complex:R-MMU-174432] Processive complex loaded on telomere:nicked DNA from adjacent Okazaki fragments [nucleoplasm]
precedingEvent	[Reaction:R-MMU-174441] Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand - Mus musculus
regulatedBy	[PositiveRegulation:9878146] Positive regulation by 'WRN [nucleoplasm]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-174446
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-174437] Removal of the Flap Intermediate from the C-strand
(precedingEvent)	[Reaction:R-MMU-174456] Joining of adjacent Okazaki fragments of the C-strand
(inferredTo)	[Reaction:R-HSA-174446] Removal of remaining Flap from the C-strand