Reactome | IDS hydrolyses Heparan sulfate chain(5)

Schema > Reaction > Entries

IDS hydrolyses Heparan sulfate chain(5) Show undefined attributes

catalystActivity	[CatalystActivity:9916446] iduronate-2-sulfatase activity of IDS dimer [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9916448
displayName	IDS hydrolyses Heparan sulfate chain(5)
eventOf	[Pathway:R-MMU-2024096] HS-GAG degradation - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2090037] IDUA hydrolyses Heparan sulfate chain(6) - Mus musculus
inferredFrom	[Reaction:R-HSA-1678650] IDS hydrolyses Heparan sulfate chain(5) - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [SimpleEntity:R-ALL-2090080] Heparan sulfate chain(5) [lysosomal lumen]
isInDisease	false
isInferred	true
name	IDS hydrolyses Heparan sulfate chain(5)
output	[SimpleEntity:R-ALL-2090055] Heparan sulfate chain(6) [lysosomal lumen] [SimpleEntity:R-ALL-1606845] SO4(2-) [lysosomal lumen]
precedingEvent	[Reaction:R-MMU-1678742] NAGLU hydrolyses Heparan sulfate chain(4) - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1678650
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2024096] HS-GAG degradation
(precedingEvent)	[Reaction:R-MMU-2090037] IDUA hydrolyses Heparan sulfate chain(6)
(inferredTo)	[Reaction:R-HSA-1678650] IDS hydrolyses Heparan sulfate chain(5)