Reactome | Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)

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Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) Show undefined attributes

catalystActivity	[CatalystActivity:9874542] long-chain fatty acid-CoA ligase activity of SLC27A5 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9874544
displayName	Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)
eventOf	[Pathway:R-MMU-159418] Recycling of bile acids and salts - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine - Mus musculus
inferredFrom	[Reaction:R-HSA-159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-194096] CCA,CDCA [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	true
name	Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [DefinedSet:R-ALL-194073] choloyl-CoA; chenodeoxycholoyl-CoA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-MMU-194130] Transport (influx) of bile salts and acids by OATP-A - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-159425
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-159418] Recycling of bile acids and salts
(precedingEvent)	[Reaction:R-MMU-159431] Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
(inferredTo)	[Reaction:R-HSA-159425] Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)

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