Reactome | ISGylation of protein phosphatase 1 beta (PP2CB)

Schema > Reaction > Entries

ISGylation of protein phosphatase 1 beta (PP2CB) Show undefined attributes

catalystActivity	[CatalystActivity:9908389] ubiquitin-protein transferase activity of ISG15:UBCH8:ISG15 E3 ligase [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9908427
displayName	ISGylation of protein phosphatase 1 beta (PP2CB)
eventOf	[Pathway:R-MMU-1169408] ISG15 antiviral mechanism - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1169405] ISGylation of protein phosphatase 1 beta (PP2CB) - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-1169383] ISG15:UBCH8:ISG15 E3 ligase [cytosol] [EntityWithAccessionedSequence:R-MMU-1169375] PPM1B [cytosol]
isInDisease	false
isInferred	true
name	ISGylation of protein phosphatase 1 beta (PP2CB)
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [CandidateSet:R-MMU-1169381] ISG15 E3 ligases [cytosol] [Complex:R-MMU-1169391] ISGylated PP2CB [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol] [EntityWithAccessionedSequence:R-MMU-936014] Ube2l6 [cytosol]
precedingEvent	[Reaction:R-MMU-1169403] Interaction of E3 ligase with ISG15:E2 complex - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1169405
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1169408] ISG15 antiviral mechanism
(inferredTo)	[Reaction:R-HSA-1169405] ISGylation of protein phosphatase 1 beta (PP2CB)