Reactome | TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane]

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TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9697748] cysteine-type endopeptidase activity of TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-HSA-9697750] RIPK1 is cleaved by CASP8:FLIP(L) - Homo sapiens
created	[InstanceEdit:9697745] Shamovsky, Veronica, 2020-08-20
dbId	9697746
displayName	TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3465404] CASP8(1-374) [cytosol] [EntityWithAccessionedSequence:R-HSA-3465408] CFLAR(1-376) [cytosol] [Complex:R-HSA-140977] TRADD:TRAF2:RIPK1:FADD [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-9697746] TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Mus musculus [Complex:R-RNO-9697746] TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Rattus norvegicus [Complex:R-CFA-3465431] DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Canis familiaris [Complex:R-BTA-9697746] TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Bos taurus [Complex:R-SSC-9697746] TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Sus scrofa [Complex:R-GGA-9697746] TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] - Gallus gallus
isChimeric	false
name	TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L)
producedByEvent	[BlackBoxEvent:R-HSA-9697747] Caspase-8 and FLIP(L) processing at TNFR signaling complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9697746

Referrals

(input)	[BlackBoxEvent:R-HSA-9697750] RIPK1 is cleaved by CASP8:FLIP(L)
(physicalEntity)	[CatalystActivity:9697748] cysteine-type endopeptidase activity of TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane]
(output)	[BlackBoxEvent:R-HSA-9697747] Caspase-8 and FLIP(L) processing at TNFR signaling complex

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