Reactome | RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9693949] Shamovsky, Veronica, 2020-07-08
dbId	9693943
displayName	RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol]
hasComponent	[Complex:R-HSA-5218862] RIPK1:RIPK3 [cytosol] [DefinedSet:R-HSA-9694028] small molecule inhibitors of RIPK1, RIPK3 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9693943] RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] - Mus musculus [Complex:R-RNO-9693943] RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] - Rattus norvegicus [Complex:R-CFA-9693943] RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] - Canis familiaris [Complex:R-BTA-9693943] RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] - Bos taurus [Complex:R-SSC-9693943] RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] - Sus scrofa
isChimeric	false
modified	[InstanceEdit:9793348] Shamovsky, Veronica, 2022-06-10
name	RIPK1:RIPK3:sorafenib, ponatinib, pazopanib
negativelyRegulates	[NegativeRegulation:9693970] Negative regulation by 'RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol]'
producedByEvent	[Reaction:R-HSA-9693978] Small molecule inhibitor binds RIPK1, RIPK3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9693943

(output)	[Reaction:R-HSA-9693978] Small molecule inhibitor binds RIPK1, RIPK3
(regulator)	[NegativeRegulation:9693970] Negative regulation by 'RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol]'