Reactome | FLT3 F594V [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9691118] FLT3 F594V dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:9691063] Rothfels, Karen, 2020-06-08
crossReference	[DatabaseIdentifier:9691026] COSMIC:COSV54051445
dbId	9691061
disease	[Disease:1500689] cancer [Disease:9630839] acute myeloid leukemia
displayName	FLT3 F594V [plasma membrane]
endCoordinate	993
hasModifiedResidue	[ReplacedResidue:9691038] L-phenylalanine 594 replaced with L-valine
inDisease	true
name	FLT3 F594V STK-1
referenceEntity	[ReferenceGeneProduct:54914] UniProt:P36888 FLT3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9691061
startCoordinate	27

(hasCandidate)	[CandidateSet:R-HSA-9691152] juxtamembrane domain mutants of FLT3 [plasma membrane]
(hasComponent)	[Complex:R-HSA-9691118] FLT3 F594V dimer [plasma membrane]

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