Reactome | ALPK1:ADP-heptose:TIFA dimer [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9645389] protein serine/threonine kinase activity of ALPK1:ADP-heptose:TIFA dimer [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9645535] ALPK1 phosphorylates TIFA - Homo sapiens
created	[InstanceEdit:9645472] Shamovsky, Veronica, 2019-05-12
dbId	9645525
displayName	ALPK1:ADP-heptose:TIFA dimer [cytosol]
hasComponent	[Complex:R-HSA-9645521] ALPK1:ADP heptose [cytosol] [Complex:R-HSA-9645383] TIFA:TIFA [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Mus musculus [Complex:R-RNO-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Rattus norvegicus [Complex:R-CFA-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Canis familiaris [Complex:R-BTA-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Bos taurus [Complex:R-SSC-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Sus scrofa [Complex:R-XTR-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Xenopus tropicalis [Complex:R-GGA-9645525] ALPK1:ADP-heptose:TIFA dimer [cytosol] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:9645451] Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
name	ALPK1:ADP-heptose:TIFA dimer
producedByEvent	[Reaction:R-HSA-9645524] ALPK1:ADP-heptose binds TIFA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9645525

(output)	[Reaction:R-HSA-9645524] ALPK1:ADP-heptose binds TIFA
(input)	[Reaction:R-HSA-9645535] ALPK1 phosphorylates TIFA
(physicalEntity)	[CatalystActivity:9645389] protein serine/threonine kinase activity of ALPK1:ADP-heptose:TIFA dimer [cytosol]