Reactome | ABCA6 gene expression is stimulated by FOXO1,FOXO3

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9625975] Orlic-Milacic, Marija, 2018-10-23
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9625080] Orlic-Milacic, Marija, 2018-10-18
dbId	9625092
displayName	ABCA6 gene expression is stimulated by FOXO1,FOXO3
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
eventOf	[Pathway:R-HSA-9615017] FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9625094] ABCA6 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9625090] FoxO regulates expression of ABCA6, an intracellular ATP-binding-cassette transporter responsive to cholesterol
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ABCA6 gene expression is stimulated by FOXO1,FOXO3
output	[EntityWithAccessionedSequence:R-HSA-383200] ABCA6 [plasma membrane]
precedingEvent	[Reaction:R-HSA-9625091] FOXO1,FOXO3 bind ABCA6 gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9625088] Positive gene expression regulation by 'FOXO1,FOXO3:ABCA6 gene [nucleoplasm]'
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9626980] Donlon, Timothy, 2018-10-23
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9625092
summation	[Summation:9625083] FOXO1 and FOXO3 directly stimulate transcription of the ABCA...

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