Reactome | AGRP gene expression is stimulated by FOXO1

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9624371] Orlic-Milacic, Marija, 2018-10-11
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9623030] Orlic-Milacic, Marija, 2018-10-02
dbId	9623023
displayName	AGRP gene expression is stimulated by FOXO1
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
eventOf	[Pathway:R-HSA-9615017] FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-9623027] Agrp gene expression is stimulated by Foxo1 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9623045] AGRP gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AGRP gene expression is stimulated by FOXO1
output	[EntityWithAccessionedSequence:R-HSA-9623016] AGRP [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9623018] FOXO1 binds AGRP gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9623040] Positive gene expression regulation by 'FOXO1:AGRP gene [nucleoplasm]'
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9625979] Donlon, Timothy, 2018-10-17 [InstanceEdit:9626974] Bertaggia, Enrico, 2018-10-26
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9623023
summation	[Summation:9623056] Based on studies in mice, FOXO1 directly promotes transcript...

(hasEvent)	[Pathway:R-HSA-9615017] FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
(inferredTo)	[BlackBoxEvent:R-MMU-9623027] Agrp gene expression is stimulated by Foxo1

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