Reactome | viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:918231] protein serine/threonine kinase activity of viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane]
compartment	[Compartment:17906] mitochondrial outer membrane
consumedByEvent	[Reaction:R-HSA-918229] Phosphorylation and release of IRF3/IRF7 - Homo sapiens
created	[InstanceEdit:918198] Garapati, P V, 2010-08-02
dbId	918199
displayName	viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane]
hasComponent	[DefinedSet:R-HSA-450317] IRF3,IRF7 [cytosol] [Complex:R-HSA-9710999] viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2x(TBK1/IKBKE) [mitochondrial outer membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
modified	[InstanceEdit:9835860] Shamovsky, Veronica, 2023-05-18
name	viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 dsRNA:RIG-1/MDA5:IPS-1:Ub-TRAF3:TBK1,IKBKE:IRF3,IRF7
producedByEvent	[Reaction:R-HSA-918232] Recruitment of IRF3,IRF7 - Homo sapiens
relatedSpecies	[Species:5621375] Hepatitis C Virus [Species:9013948] Measles virus [Species:5617433] Rotavirus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-918199

(output)	[Reaction:R-HSA-918232] Recruitment of IRF3,IRF7
(input)	[Reaction:R-HSA-918229] Phosphorylation and release of IRF3/IRF7
(physicalEntity)	[CatalystActivity:918231] protein serine/threonine kinase activity of viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane]

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