Reactome | MECP2 binds DGCR8

Schema > Reaction > Entries

authored	[InstanceEdit:9024208] Orlic-Milacic, Marija, 2017-10-02
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9022306] Orlic-Milacic, Marija, 2017-09-22
dbId	9022315
displayName	MECP2 binds DGCR8
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:1301564] negative regulation of primary miRNA processing
inferredFrom	[Reaction:R-MMU-9022302] Mecp2 binds Dgcr8 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-1482509] DGCR8 [nucleoplasm] [CandidateSet:R-HSA-9022332] p-S80-MECP2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MECP2 binds DGCR8
output	[Complex:R-HSA-9022340] MECP2:DGCR8 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9022314] HIPK2 phosphorylates MECP2 - Homo sapiens
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9022315
summation	[Summation:9022303] Based on studies in mice, MECP2, phosphorylated at serine re...

(hasEvent)	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
(inferredTo)	[Reaction:R-MMU-9022302] Mecp2 binds Dgcr8

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