Reactome | LHX2 binds to ROBO2 gene locus

Schema > Reaction > Entries

authored	[InstanceEdit:9009836] Orlic-Milacic, Marija, 2017-06-23
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9011078] Orlic-Milacic, Marija, 2017-06-29
dbId	9011077
displayName	LHX2 binds to ROBO2 gene locus
edited	[InstanceEdit:9014888] Orlic-Milacic, Marija, 2017-08-04
eventOf	[Pathway:R-HSA-9010553] Regulation of expression of SLITs and ROBOs - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9010523] ROBO2 gene transcription is stimulated by HOXA2 and inhibited by LHX2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9011075] Lhx2 binds to Robo2 gene locus - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-9011100] LHX2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9010496] ROBO2 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LHX2 binds to ROBO2 gene locus
output	[Complex:R-HSA-9011108] LHX2:ROBO2 gene [nucleoplasm]
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9011077
summation	[Summation:9011133] Based on studies in mice, a LIM-homeodomain transcription fa...

(hasEvent)	[Pathway:R-HSA-9010553] Regulation of expression of SLITs and ROBOs
(precedingEvent)	[BlackBoxEvent:R-HSA-9010523] ROBO2 gene transcription is stimulated by HOXA2 and inhibited by LHX2
(inferredTo)	[Reaction:R-MMU-9011075] Lhx2 binds to Robo2 gene locus

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