Reactome | E2F1:(TFDP1,TFDP2) [nucleoplasm]

Schema > Complex > Entries

E2F1:(TFDP1,TFDP2) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9007509] E2F1:(TFDP1,TFDP2):APAF1 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9617780] MYC gene:E2F1:(TFDP1,TFDP2) [nucleoplasm] - Homo sapiens [Complex:R-HSA-9617790] MYC gene:CEBPA:E2F1:(TFDP1,TFDP2) [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9007514] E2F1 binds APAF1 gene promoter - Homo sapiens [Reaction:R-HSA-9007561] E2F1 binds RAD51 gene promoter - Homo sapiens [Reaction:R-HSA-9618586] E2F1 binds the promoter of the MYC gene - Homo sapiens
created	[InstanceEdit:9007510] Orlic-Milacic, Marija, 2017-05-31
crossReference	[DatabaseIdentifier:11892041] ComplexPortal:CPX-175 [DatabaseIdentifier:11892077] ComplexPortal:CPX-1972
dbId	9007512
displayName	E2F1:(TFDP1,TFDP2) [nucleoplasm]
hasComponent	[CandidateSet:R-HSA-9007508] (TFDP1,TFDP2) [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-68639] E2F1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Mus musculus [Complex:R-RNO-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Canis familiaris [Complex:R-BTA-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Bos taurus [Complex:R-SSC-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Sus scrofa [Complex:R-XTR-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Gallus gallus [Complex:R-DME-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Drosophila melanogaster [Complex:R-DDI-9007512] E2F1:(TFDP1,TFDP2) [nucleoplasm] - Dictyostelium discoideum
isChimeric	false
literatureReference	[LiteratureReference:9007498] E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1
modified	[InstanceEdit:11891188] Wright, Adam, 2024-03-11
name	E2F1:(TFDP1,TFDP2)
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9007512

Referrals

(input)	[Reaction:R-HSA-9618586] E2F1 binds the promoter of the MYC gene [Reaction:R-HSA-9007514] E2F1 binds APAF1 gene promoter [Reaction:R-HSA-9007561] E2F1 binds RAD51 gene promoter
(hasComponent)	[Complex:R-HSA-9617790] MYC gene:CEBPA:E2F1:(TFDP1,TFDP2) [nucleoplasm] [Complex:R-HSA-9617780] MYC gene:E2F1:(TFDP1,TFDP2) [nucleoplasm] [Complex:R-HSA-9007509] E2F1:(TFDP1,TFDP2):APAF1 gene [nucleoplasm] [Complex:R-HSA-9007572] E2F1:(TFDP1,TFDP2):RAD51 gene [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:R-HSA-9007583] Positive gene expression regulation by 'E2F1:(TFDP1,TFDP2):RAD51 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-9007511] Positive gene expression regulation by 'E2F1:(TFDP1,TFDP2):APAF1 gene [nucleoplasm]'

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