Reactome | E2F1 binds the CDT1 gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:113696] Gopinathrao, G, 2004-06-16 19:22:00
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8961944] Orlic-Milacic, Marija, 2017-02-06
dbId	8961946
displayName	E2F1 binds the CDT1 gene promoter
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
eventOf	[Pathway:R-HSA-69205] G1/S-Specific Transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8961952] CDT1 gene expression is stimulated by E2F1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8961940] CDT1 gene [nucleoplasm] [Complex:R-HSA-68653] E2F1:TFDP1,TFDP2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:113627] Regulation of Geminin and Cdt1 expression by E2F transcription factors
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E2F1 binds the CDT1 gene promoter
output	[Complex:R-HSA-8961945] E2F1:TFDP1,TFDP2:CDT1 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes - Homo sapiens
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:113697] Bosco, G, 2004-06-16 19:24:21
revised	[InstanceEdit:617365] Matthews, L, 2010-04-21
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8961946
summation	[Summation:8961947] E2F1 binds to E2F binding sites in the promoter of the CDT1 ...

(precedingEvent)	[BlackBoxEvent:R-HSA-8961952] CDT1 gene expression is stimulated by E2F1
(hasEvent)	[Pathway:R-HSA-69205] G1/S-Specific Transcription

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