Reactome | RUNX3 Regulates Immune Response and Cell Migration

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RUNX3 Regulates Immune Response and Cell Migration Show undefined attributes

authored	[InstanceEdit:8951943] Orlic-Milacic, Marija, 2016-12-12
created	[InstanceEdit:8949277] Orlic-Milacic, Marija, 2016-11-21
dbId	8949275
displayName	RUNX3 Regulates Immune Response and Cell Migration
edited	[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
eventOf	[Pathway:R-HSA-8878159] Transcriptional regulation by RUNX3 - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-8949276] RUNX3:CBFB binds the RORC gene promoter - Homo sapiens [BlackBoxEvent:R-HSA-8949301] RORC gene expression is stimulated by RUNX3:CBFB - Homo sapiens [Reaction:R-HSA-8949335] RUNX3:CBFB binds the ITGAL gene,(ITGA4 gene) promoter - Homo sapiens [BlackBoxEvent:R-HSA-8949343] ITGAL gene,(ITGA4 gene) expression is stimulated by RUNX3:CBFB - Homo sapiens [BlackBoxEvent:R-HSA-8952442] SPP1 gene expression is stimulated by RUNX3 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8949254] Runx3 specifies lineage commitment of innate lymphoid cells [LiteratureReference:8952434] RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma [LiteratureReference:8949257] RUNX3 regulates the activity of the CD11a and CD49d integrin gene promoters [LiteratureReference:8952853] The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX3 Regulates Immune Response and Cell Migration
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31 [InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-8949275
summation	[Summation:8952856] RUNX3-mediated transcription regulates development of immune...

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[Pathway:R-HSA-8878159] Transcriptional regulation by RUNX3