Reactome | TFAP2A in complex with DEK binds the APOE gene promoter

Schema > Reaction > Entries

TFAP2A in complex with DEK binds the APOE gene promoter Show undefined attributes

authored	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8869579] Orlic-Milacic, Marija, 2016-05-05
dbId	8869575
displayName	TFAP2A in complex with DEK binds the APOE gene promoter
edited	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
eventOf	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8869590] The APOE gene transcription is stimulated by the complex of TFAP2A homodimer and DEK - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8869591] APOE gene [nucleoplasm] [Complex:R-HSA-8869593] DEK:TFAP2A homodimer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8869583] Transcriptional activation by AP-2alpha is modulated by the oncogene DEK
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TFAP2A in complex with DEK binds the APOE gene promoter
output	[Complex:R-HSA-8869574] DEK:TFAP2A homodimer:APOE gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8869580] DEK binds TFAP2A homodimers - Homo sapiens
releaseDate	2016-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8869464] Zarelli, Valeria E, 2016-05-04 [InstanceEdit:8869466] Dawid, Igor B, 2016-05-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8869575
summation	[Summation:8869582] DEK is recruited to the APOE gene promoter via its interacti...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-8869590] The APOE gene transcription is stimulated by the complex of TFAP2A homodimer and DEK
(hasEvent)	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

Cite Us!