Reactome | SL (surrogate light chain) binds IgH to form pre-BCR

Schema > Reaction > Entries

authored	[InstanceEdit:8858505] Garapati, Phani Vijay, 2016-02-19
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8858505] Garapati, Phani Vijay, 2016-02-19
dbId	8858498
displayName	SL (surrogate light chain) binds IgH to form pre-BCR
edited	[InstanceEdit:8858505] Garapati, Phani Vijay, 2016-02-19
eventOf	[Pathway:R-HSA-202733] Cell surface interactions at the vascular wall - Homo sapiens
input	2 × [Complex:R-HSA-983669] IgM Heavy Chain [plasma membrane] 2 × [Complex:R-HSA-983678] Pre-B Cell Surrogate Light Chain [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8858445] The surrogate light chain in B-cell development
modified	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
name	SL (surrogate light chain) binds IgH to form pre-BCR
orthologousEvent	[Reaction:R-SSC-8858498] SL (surrogate light chain) binds IgH to form pre-BCR - Sus scrofa [Reaction:R-RNO-8858498] SL (surrogate light chain) binds IgH to form pre-BCR - Rattus norvegicus [Reaction:R-MMU-8858498] SL (surrogate light chain) binds IgH to form pre-BCR - Mus musculus
output	[Complex:R-HSA-983671] Immunoglobulin Mu with Surrogate Light Chain [plasma membrane]
releaseDate	2016-12-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8938894] Meldal, Birgit, 2016-09-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8858498
summation	[Summation:8858461] The pre-BCR is a heterodimer composed of an immunoglobulin (...

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