Reactome | VENTX binds the CDKN2A gene

Schema > Reaction > Entries

authored	[InstanceEdit:9652372] Orlic-Milacic, Marija, 2019-06-28
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8853923] Orlic-Milacic, Marija, 2016-01-25
dbId	8853920
displayName	VENTX binds the CDKN2A gene
edited	[InstanceEdit:9666043] Orlic-Milacic, Marija, 2019-11-01
eventOf	[Pathway:R-HSA-8853884] Transcriptional Regulation by VENTX - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8853921] VENTX stimulates p16-INK4A transcription - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3200017] CDKN2A gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8853887] VENTX [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8853914] VentX trans-activates p53 and p16ink4a to regulate cellular senescence
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	VENTX binds the CDKN2A gene
output	[Complex:R-HSA-8853922] VENTX:CDKN2A Gene [nucleoplasm]
releaseDate	2019-12-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9666044] Vegi, Naidu M, 2019-10-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8853920
summation	[Summation:8867906] VENTX binds to the CDKN2A promoter that regulates the expres...

(hasEvent)	[Pathway:R-HSA-8853884] Transcriptional Regulation by VENTX
(precedingEvent)	[BlackBoxEvent:R-HSA-8853921] VENTX stimulates p16-INK4A transcription

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