Reactome | p-6Y-FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853223] p-6Y FGFR2(22-767)-CCAR(51-923) fusion dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
dbId	8853141
disease	[Disease:1981182] lung squamous cell carcinoma
displayName	p-6Y-FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane]
endCoordinate	767
hasModifiedResidue	[FragmentInsertionModification:8853115] Insertion of residues 51 to 923 at 768 from UniProt:Q8N163 CCAR2 [ModifiedResidue:8853097] O4'-phospho-L-tyrosine at 466 [ModifiedResidue:8853091] O4'-phospho-L-tyrosine at 586 [ModifiedResidue:8853096] O4'-phospho-L-tyrosine at 588 [ModifiedResidue:8853090] O4'-phospho-L-tyrosine at 656 [ModifiedResidue:8853093] O4'-phospho-L-tyrosine at 657 [ModifiedResidue:8853088] O4'-phospho-L-tyrosine at 733
inDisease	true
literatureReference	[LiteratureReference:8852972] Identification of targetable FGFR gene fusions in diverse cancers
modified	[InstanceEdit:9832293] Orlic-Milacic, Marija, 2023-03-30
name	p-6Y-FGFR2(22-767)-CCAR(51-923) fusion p-6Y-FGFR2(22-767)-KIAA1967(51-923) fusion
referenceEntity	[ReferenceGeneProduct:403305] UniProt:P21802 FGFR2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853141
startCoordinate	22

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