Reactome | Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2

Schema > Reaction > Entries

Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 Show undefined attributes

catalystActivity	[CatalystActivity:77336] acyl-CoA dehydrogenase activity of ACADM tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:11881024] Rhea:30944
dbId	77338
displayName	Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2
eventOf	[Pathway:R-HSA-77348] Beta oxidation of octanoyl-CoA to hexanoyl-CoA - Homo sapiens
followingEvent	[Reaction:R-HSA-77333] trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA - Homo sapiens [Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Homo sapiens
input	[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix] [SimpleEntity:R-ALL-77337] Octanoyl-CoA [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:77398] On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein. [LiteratureReference:70739] Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2
orthologousEvent	[Reaction:R-CEL-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Caenorhabditis elegans [Reaction:R-DME-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Drosophila melanogaster [Reaction:R-GGA-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Gallus gallus [Reaction:R-SSC-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Sus scrofa [Reaction:R-BTA-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Bos taurus [Reaction:R-CFA-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Canis familiaris [Reaction:R-RNO-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Rattus norvegicus [Reaction:R-MMU-77338] Octanoyl-CoA+FAD<=>trans-Oct-2-enoyl-CoA+FADH2 - Mus musculus
output	[SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix] [SimpleEntity:R-ALL-77332] trans-Oct-2-enoyl-CoA [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-77340] 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-77338
summation	[Summation:179006] At the beginning of this reaction, 1 molecule of 'Octanoyl-C...

Referrals

(hasEvent)	[Pathway:R-HSA-77348] Beta oxidation of octanoyl-CoA to hexanoyl-CoA
(precedingEvent)	[Reaction:R-HSA-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF [Reaction:R-HSA-77333] trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA