Reactome | dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)

Schema > Reaction > Entries

dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) Show undefined attributes

catalystActivity	[CatalystActivity:74206] deoxynucleoside kinase activity of DGUOK dimer [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9643208] nucleoside kinase activity of DGUOK dimer [mitochondrial matrix] Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:74183] Jassal, B, 2003-07-17 08:31:43
dbId	74207
displayName	dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)
eventOf	[Pathway:R-HSA-74217] Purine salvage - Homo sapiens
followingEvent	[Reaction:R-HSA-73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1) - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [DefinedSet:R-ALL-500224] dA, dG, dI [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:109711] Cloning and expression of human deoxyguanosine kinase cDNA [LiteratureReference:109719] Properties of a highly purified mitochondrial deoxyguanosine kinase [LiteratureReference:109712] Structural basis for substrate specificities of cellular deoxyribonucleoside kinases
modified	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
name	dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK)
orthologousEvent	[Reaction:R-XTR-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Xenopus tropicalis [Reaction:R-DRE-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Danio rerio [Reaction:R-SSC-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Sus scrofa [Reaction:R-BTA-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Bos taurus [Reaction:R-CFA-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Canis familiaris [Reaction:R-RNO-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Rattus norvegicus [Reaction:R-MMU-74207] dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) - Mus musculus
output	[SimpleEntity:R-ALL-113581] ADP [mitochondrial matrix] [DefinedSet:R-ALL-500222] dAMP, dGMP, dIMP [mitochondrial matrix]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:504064] D'Eustachio, P, 2010-02-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-74207
summation	[Summation:178290] Mitochondrial deoxyguanosine kinase (DGUOK) catalyzes the re...

Referrals

(hasEvent)	[Pathway:R-HSA-74217] Purine salvage
(precedingEvent)	[Reaction:R-HSA-73788] (d)GMP + ATP <=> (d)GDP + ADP (GUK1)