Reactome | SLC35B2,3 transport cytosolic PAPS to Golgi lumen

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SLC35B2,3 transport cytosolic PAPS to Golgi lumen Show undefined attributes

authored	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
catalystActivity	[CatalystActivity:741439] 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity of SLC35B2,3 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen [Compartment:70101] cytosol
created	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
dbId	741449
displayName	SLC35B2,3 transport cytosolic PAPS to Golgi lumen
edited	[InstanceEdit:741453] Jassal, Bijay, 2010-05-14
eventOf	[Pathway:R-HSA-727802] Transport of nucleotide sugars - Homo sapiens [Pathway:R-HSA-174362] Transport and synthesis of PAPS - Homo sapiens
followingEvent	[Reaction:R-HSA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII - Homo sapiens [Reaction:R-HSA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2 - Homo sapiens [Reaction:R-HSA-2018659] Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 - Homo sapiens [Reaction:R-HSA-1971483] Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 - Homo sapiens [Reaction:R-HSA-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate - Homo sapiens [Reaction:R-HSA-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS - Homo sapiens [Reaction:R-HSA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin - Homo sapiens [Reaction:R-HSA-2076611] HS3STs sulfate GlcN at C3 in heparan sulfate - Homo sapiens [Reaction:R-HSA-2022860] NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) - Homo sapiens [Reaction:R-HSA-2076508] HS2ST1 sulfates IdoA at C2 in heparan sulfate - Homo sapiens [Reaction:R-HSA-2076383] HS3ST1 sulfates GlcN at C3 in heparan sulfate - Homo sapiens [Reaction:R-HSA-2046175] Further sulfation on galactose residues produces KSPG - Homo sapiens [Reaction:R-HSA-2046222] CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG - Homo sapiens [Reaction:R-HSA-2018682] CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:5263389] 5'-adenylyl sulfate transmembrane transport
input	[SimpleEntity:R-ALL-158471] PAPS [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:742342] Identification and partial purification of PAPS translocase [LiteratureReference:741444] Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter [LiteratureReference:742372] Molecular cloning and characterization of a novel 3'-phosphoadenosine 5'-phosphosulfate transporter, PAPST2
modified	[InstanceEdit:10818988] Wright, Adam, 2024-03-08
name	SLC35B2,3 transport cytosolic PAPS to Golgi lumen
orthologousEvent	[Reaction:R-DDI-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Dictyostelium discoideum [Reaction:R-CEL-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Caenorhabditis elegans [Reaction:R-DME-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Drosophila melanogaster [Reaction:R-GGA-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Gallus gallus [Reaction:R-DRE-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Danio rerio [Reaction:R-SSC-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Sus scrofa [Reaction:R-BTA-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Bos taurus [Reaction:R-CFA-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Canis familiaris [Reaction:R-RNO-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Rattus norvegicus [Reaction:R-MMU-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Mus musculus
output	[SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
precedingEvent	[Reaction:R-HSA-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Homo sapiens
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9774232] Hill, David P, 2022-05-19
revised	[InstanceEdit:9774231] D'Eustachio, Peter, 2022-05-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-741449
summation	[Summation:741442] The human gene SLC35B2 encodes the adenosine 3'-phospho 5'-p...

Referrals

(precedingEvent)

[Reaction:R-HSA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII
[Reaction:R-HSA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2
[Reaction:R-HSA-2018659] Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15
[Reaction:R-HSA-2018682] CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains
[Reaction:R-HSA-1971483] Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13
[Reaction:R-HSA-2022061] Dermatan sulfate can be further sulfated on position 2 of iduronate
[Reaction:R-HSA-2022063] CHST14 transfers SO4(2-) to GalNAc in dermatan or DS
[Reaction:R-HSA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin
[Reaction:R-HSA-2076611] HS3STs sulfate GlcN at C3 in heparan sulfate
[Reaction:R-HSA-2022860] NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS)
[Reaction:R-HSA-2076508] HS2ST1 sulfates IdoA at C2 in heparan sulfate
[Reaction:R-HSA-2076383] HS3ST1 sulfates GlcN at C3 in heparan sulfate
[Reaction:R-HSA-2046175] Further sulfation on galactose residues produces KSPG
[Reaction:R-HSA-2046222] CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG

(hasEvent)

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