Reactome | acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+

Schema > Reaction > Entries

acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ Show undefined attributes

catalystActivity	[CatalystActivity:74155] 3-hydroxybutyrate dehydrogenase activity of BDH1 tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:73908] Gopinathrao, G, 2003-08-20 08:52:29
crossReference	[DatabaseIdentifier:11880853] Rhea:20523
dbId	73912
displayName	acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+
eventOf	[Pathway:R-HSA-77111] Synthesis of Ketone Bodies - Homo sapiens
input	[SimpleEntity:R-ALL-73909] ACA [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:200046] Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ Reduction of Acetoacetate to beta-Hydroxybutyrate
orthologousEvent	[Reaction:R-SSC-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Sus scrofa [Reaction:R-SPO-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Schizosaccharomyces pombe [Reaction:R-DME-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Drosophila melanogaster [Reaction:R-GGA-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Gallus gallus [Reaction:R-XTR-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Xenopus tropicalis [Reaction:R-DRE-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Danio rerio [Reaction:R-BTA-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Bos taurus [Reaction:R-CFA-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Canis familiaris [Reaction:R-RNO-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Rattus norvegicus [Reaction:R-MMU-73912] acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ - Mus musculus
output	[SimpleEntity:R-ALL-73911] bHBA [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-74180] HMG CoA => acetoacetic acid + acetyl CoA - Homo sapiens
releaseDate	2004-07-06
reverseReaction	[Reaction:R-HSA-73920] D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-73912
summation	[Summation:179135] D-beta-hydroxybutyrate dehydrogenase tetramer (BDH1) in the ...

Referrals

(hasEvent)

[Pathway:R-HSA-77111] Synthesis of Ketone Bodies