Reactome | alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+

Schema > Reaction > Entries

alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ Show undefined attributes

authored	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
catalystActivity	[CatalystActivity:508540] L-aminoadipate-semialdehyde dehydrogenase activity of ALDH7A1 tetramer [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9643397] L-aminoadipate-semialdehyde dehydrogenase activity of ALDH7A1 tetramer [mitochondrial matrix] Mutations in antiquitin in individuals with pyridoxine-dependent seizures
category	transition
compartment	[Compartment:5460] mitochondrial matrix
crossReference	[DatabaseIdentifier:11880938] Rhea:12309
dbId	70941
displayName	alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+
edited	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
eventOf	[Pathway:R-HSA-71064] Lysine catabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-70952] alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate - Homo sapiens
input	[SimpleEntity:R-ALL-113556] 2AMAS [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:508571] Mutations in antiquitin in individuals with pyridoxine-dependent seizures [LiteratureReference:508537] Is antiquitin a mitochondrial Enzyme?
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+
orthologousEvent	[Reaction:R-BTA-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Bos taurus [Reaction:R-DDI-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Dictyostelium discoideum [Reaction:R-CEL-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Caenorhabditis elegans [Reaction:R-DME-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Drosophila melanogaster [Reaction:R-GGA-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Gallus gallus [Reaction:R-XTR-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Xenopus tropicalis [Reaction:R-DRE-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Danio rerio [Reaction:R-SSC-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Sus scrofa [Reaction:R-CFA-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Canis familiaris [Reaction:R-RNO-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Rattus norvegicus [Reaction:R-MMU-70941] alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ - Mus musculus
output	[SimpleEntity:R-ALL-508531] 2AMA [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-70940] saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ - Homo sapiens [BlackBoxEvent:R-HSA-6783883] P6C transforms to 2AMAS - Homo sapiens [Reaction:R-HSA-5696408] PXLP-K278-PHYKPL tetramer hydrolyses 5PHL - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-70941
summation	[Summation:178459] Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) catal...

Referrals

(hasEvent)	[Pathway:R-HSA-71064] Lysine catabolism
(precedingEvent)	[Reaction:R-HSA-70952] alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate

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