Reactome | histidine => urocanate + NH4+

Schema > Reaction > Entries

histidine => urocanate + NH4+ Show undefined attributes

authored	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
catalystActivity	[CatalystActivity:70898] histidine ammonia-lyase activity of HAL [cytosol]
catalystActivityReference	[CatalystActivityReference:9643422] histidine ammonia-lyase activity of HAL [cytosol] Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene
category	transition
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:11880961] Rhea:21233
dbId	70899
displayName	histidine => urocanate + NH4+
edited	[InstanceEdit:73677] D'Eustachio, P, 2003-06-24 00:00:00
eventOf	[Pathway:R-HSA-70921] Histidine catabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-70903] urocanate + H2O => 4-imidazolone-5-propionate - Homo sapiens
input	[SimpleEntity:R-ALL-29612] L-His [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:200265] Molecular characterization of histidinemia: identification of four missense mutations in the histidase gene
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	histidine => urocanate + NH4+
orthologousEvent	[Reaction:R-DDI-70899] histidine => urocanate + NH4+ - Dictyostelium discoideum [Reaction:R-CEL-70899] histidine => urocanate + NH4+ - Caenorhabditis elegans [Reaction:R-GGA-70899] histidine => urocanate + NH4+ - Gallus gallus [Reaction:R-XTR-70899] histidine => urocanate + NH4+ - Xenopus tropicalis [Reaction:R-DRE-70899] histidine => urocanate + NH4+ - Danio rerio [Reaction:R-SSC-70899] histidine => urocanate + NH4+ - Sus scrofa [Reaction:R-BTA-70899] histidine => urocanate + NH4+ - Bos taurus [Reaction:R-CFA-70899] histidine => urocanate + NH4+ - Canis familiaris [Reaction:R-RNO-70899] histidine => urocanate + NH4+ - Rattus norvegicus [Reaction:R-MMU-70899] histidine => urocanate + NH4+ - Mus musculus
output	[SimpleEntity:R-ALL-31633] NH4+ [cytosol] [SimpleEntity:R-ALL-30721] UCA [cytosol]
precedingEvent	[Reaction:R-HSA-8932851] PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-70899
summation	[Summation:178862] Cytosolic histidine ammonia lyase (HAL) catalyzes the reacti...

Referrals

(precedingEvent)	[Reaction:R-HSA-70903] urocanate + H2O => 4-imidazolone-5-propionate
(hasEvent)	[Pathway:R-HSA-70921] Histidine catabolism