Reactome | RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN

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RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN Show undefined attributes

authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
category	binding
compartment	[Compartment:263163] trans-Golgi network membrane
created	[InstanceEdit:6814677] Rothfels, Karen, 2015-11-27
dbId	6814675
displayName	RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
eventOf	[Pathway:R-HSA-6811440] Retrograde transport at the Trans-Golgi-Network - Homo sapiens
followingEvent	[Reaction:R-HSA-6814670] ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation - Homo sapiens
input	[Complex:R-HSA-6814666] RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3 [transport vesicle] [Complex:R-HSA-6814649] RHOBTB3:ATP [trans-Golgi network membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6814579] Rab9 functions in transport between late endosomes and the trans Golgi network [LiteratureReference:6814576] Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network [LiteratureReference:6814596] Visualization of Rab9-mediated vesicle transport from endosomes to the trans-Golgi in living cells [LiteratureReference:6811218] Entry at the trans-face of the Golgi [LiteratureReference:6814595] TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking [LiteratureReference:6814592] Role of Rab9 GTPase in facilitating receptor recruitment by TIP47 [LiteratureReference:6813928] A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling [LiteratureReference:6811192] A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells [LiteratureReference:8847816] A novel Rab9 effector required for endosome-to-TGN transport [LiteratureReference:6814583] RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport
modified	[InstanceEdit:10655440] Wright, Adam, 2024-03-08
name	RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN
orthologousEvent	[Reaction:R-DME-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Drosophila melanogaster [Reaction:R-GGA-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Gallus gallus [Reaction:R-BTA-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Bos taurus [Reaction:R-CFA-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Canis familiaris [Reaction:R-RNO-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Rattus norvegicus [Reaction:R-MMU-6814675] RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN - Mus musculus
output	[Complex:R-HSA-6814669] RAB9:GTP:PLIN3:p-RABEPK:late-endosome-to-TGN cargo:VAMP3:RHOBTB3:ATP [transport vesicle]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6814675
summation	[Summation:6814605] Retrograde traffic of mannose-6-phosphate receptors (M6PRs) ...

Referrals

(hasEvent)	[Pathway:R-HSA-6811440] Retrograde transport at the Trans-Golgi-Network
(precedingEvent)	[Reaction:R-HSA-6814670] ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation

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