Reactome | ARL1 recruits TGN Golgin homodimers

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ARL1 recruits TGN Golgin homodimers Show undefined attributes

authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
category	binding
compartment	[Compartment:263163] trans-Golgi network membrane
created	[InstanceEdit:6814092] Rothfels, Karen, 2015-11-24
dbId	6814091
displayName	ARL1 recruits TGN Golgin homodimers
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
eventOf	[Pathway:R-HSA-6811440] Retrograde transport at the Trans-Golgi-Network - Homo sapiens
input	[Complex:R-HSA-6814071] AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP [trans-Golgi network membrane] [DefinedSet:R-HSA-6814047] TGN Golgin dimers [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6813935] A novel Rab6-interacting domain defines a family of Golgi-targeted coiled-coil proteins [LiteratureReference:6813936] ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins [LiteratureReference:6813991] Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus [LiteratureReference:6813995] Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1 [LiteratureReference:6814001] The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus [LiteratureReference:6813960] Golgi recruitment of GRIP domain proteins by Arf-like GTPase 1 is regulated by Arf-like GTPase 3 [LiteratureReference:6814006] The golgin coiled-coil proteins of the Golgi apparatus [LiteratureReference:6814012] The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers [LiteratureReference:6813979] Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185 [LiteratureReference:6811192] A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells [LiteratureReference:6807641] A v-SNARE implicated in intra-Golgi transport [LiteratureReference:6813977] Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi [LiteratureReference:6811218] Entry at the trans-face of the Golgi [LiteratureReference:6813939] Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-golgi network [LiteratureReference:6814021] tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre [LiteratureReference:6813928] A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling [LiteratureReference:6814020] The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure [LiteratureReference:8847491] TMF is a golgin that binds Rab6 and influences Golgi morphology [LiteratureReference:8847463] Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	ARL1 recruits TGN Golgin homodimers
orthologousEvent	[Reaction:R-SCE-6814091] ARL1 recruits TGN Golgin homodimers - Saccharomyces cerevisiae [Reaction:R-DDI-6814091] ARL1 recruits TGN Golgin homodimers - Dictyostelium discoideum [Reaction:R-CEL-6814091] ARL1 recruits TGN Golgin homodimers - Caenorhabditis elegans [Reaction:R-DME-6814091] ARL1 recruits TGN Golgin homodimers - Drosophila melanogaster [Reaction:R-GGA-6814091] ARL1 recruits TGN Golgin homodimers - Gallus gallus [Reaction:R-XTR-6814091] ARL1 recruits TGN Golgin homodimers - Xenopus tropicalis [Reaction:R-SSC-6814091] ARL1 recruits TGN Golgin homodimers - Sus scrofa [Reaction:R-BTA-6814091] ARL1 recruits TGN Golgin homodimers - Bos taurus [Reaction:R-CFA-6814091] ARL1 recruits TGN Golgin homodimers - Canis familiaris [Reaction:R-RNO-6814091] ARL1 recruits TGN Golgin homodimers - Rattus norvegicus [Reaction:R-MMU-6814091] ARL1 recruits TGN Golgin homodimers - Mus musculus
output	[Complex:R-HSA-6814069] AcG-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:TGN Golgin dimers [trans-Golgi network membrane]
precedingEvent	[Reaction:R-HSA-6814086] ARFRP1 recruits ARL1 to the TGN - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6814091
summation	[Summation:6814036] GTP-bound ARL1, in conjunction with RAB6 and/or RAB9, is res...

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(hasEvent)

[Pathway:R-HSA-6811440] Retrograde transport at the Trans-Golgi-Network

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