Reactome | GDE1 hydrolyzes GroPIns

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GDE1 hydrolyzes GroPIns Show undefined attributes

authored	[InstanceEdit:6814856] D'Eustachio, Peter, 2015-11-28
catalystActivity	[CatalystActivity:6813736] glycerophosphoinositol glycerophosphodiesterase activity of GDE1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:6813739] D'Eustachio, Peter, 2015-11-23
crossReference	[DatabaseIdentifier:11880351] Rhea:16502
dbId	6813740
displayName	GDE1 hydrolyzes GroPIns
edited	[InstanceEdit:6814856] D'Eustachio, Peter, 2015-11-28
eventOf	[Pathway:R-HSA-6814848] Glycerophospholipid catabolism - Homo sapiens
input	[SimpleEntity:R-ALL-6813734] GroPIns [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1483090] Genomic organization, characterization, and molecular 3D model of GDE1, a novel mammalian glycerophosphoinositol phosphodiesterase [LiteratureReference:6813735] MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16 [LiteratureReference:6813742] GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	GDE1 hydrolyzes GroPIns
orthologousEvent	[Reaction:R-CEL-6813740] GDE1 hydrolyzes GroPIns - Caenorhabditis elegans [Reaction:R-DME-6813740] GDE1 hydrolyzes GroPIns - Drosophila melanogaster [Reaction:R-GGA-6813740] GDE1 hydrolyzes GroPIns - Gallus gallus [Reaction:R-XTR-6813740] GDE1 hydrolyzes GroPIns - Xenopus tropicalis [Reaction:R-DRE-6813740] GDE1 hydrolyzes GroPIns - Danio rerio [Reaction:R-SSC-6813740] GDE1 hydrolyzes GroPIns - Sus scrofa [Reaction:R-BTA-6813740] GDE1 hydrolyzes GroPIns - Bos taurus [Reaction:R-CFA-6813740] GDE1 hydrolyzes GroPIns - Canis familiaris [Reaction:R-RNO-6813740] GDE1 hydrolyzes GroPIns - Rattus norvegicus [Reaction:R-MMU-6813740] GDE1 hydrolyzes GroPIns - Mus musculus
output	[SimpleEntity:R-ALL-76114] G3P [cytosol] [SimpleEntity:R-ALL-426910] Ins [cytosol]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8847421] Jassal, Bijay, 2015-11-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6813740
summation	[Summation:6813738] GDE1 (glycerophosphodiester phosphodiesterase 1) catalyzes t...

Referrals

(hasEvent)

[Pathway:R-HSA-6814848] Glycerophospholipid catabolism