Reactome | DMGDH:FAD oxidatively demethylates DMGLY to SARC

Schema > Reaction > Entries

DMGDH:FAD oxidatively demethylates DMGLY to SARC Show undefined attributes

authored	[InstanceEdit:6797656] Jassal, Bijay, 2015-09-15
catalystActivity	[CatalystActivity:6797654] dimethylglycine dehydrogenase activity of DMGDH:FAD [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:6797656] Jassal, Bijay, 2015-09-15
dbId	6797653
displayName	DMGDH:FAD oxidatively demethylates DMGLY to SARC
edited	[InstanceEdit:6797656] Jassal, Bijay, 2015-09-15
eventOf	[Pathway:R-HSA-6798163] Choline catabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-6797913] SARDH:FAD oxidatively demethylates SARC to Gly - Homo sapiens
input	[SimpleEntity:R-ALL-6797923] DMGLY [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6797924] Structure and analysis of the human dimethylglycine dehydrogenase gene [LiteratureReference:6797925] Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	DMGDH:FAD oxidatively demethylates DMGLY to SARC
orthologousEvent	[Reaction:R-CEL-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Caenorhabditis elegans [Reaction:R-GGA-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Gallus gallus [Reaction:R-SSC-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Sus scrofa [Reaction:R-BTA-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Bos taurus [Reaction:R-CFA-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Canis familiaris [Reaction:R-RNO-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Rattus norvegicus [Reaction:R-MMU-6797653] DMGDH:FAD oxidatively demethylates DMGLY to SARC - Mus musculus
output	[SimpleEntity:R-ALL-6797920] CH2O [mitochondrial matrix] [SimpleEntity:R-ALL-6797917] SARC [mitochondrial matrix]
precedingEvent	[BlackBoxEvent:R-HSA-6797962] DMGLY translocates from cytosol to mitochondrial matrix - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6797653
summation	[Summation:6797916] Mitochondrial dimethylglycine dehydrogenase (DMGDH) is an en...

Referrals

(precedingEvent)	[Reaction:R-HSA-6797913] SARDH:FAD oxidatively demethylates SARC to Gly
(hasEvent)	[Pathway:R-HSA-6798163] Choline catabolism