Reactome | TP53 stimulates CCNG1 gene expression

Schema > BlackBoxEvent > Entries

TP53 stimulates CCNG1 gene expression Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6792487] Orlic-Milacic, Marija, 2015-08-24
dbId	6792491
displayName	TP53 stimulates CCNG1 gene expression
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804757] Regulation of TP53 Degradation - Homo sapiens
followingEvent	[Reaction:R-HSA-6792871] CCNG1 recruits PP2A-PPP2R5C to MDM2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6791403] CCNG1 Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6791406] Cyclin G is a transcriptional target of the p53 tumor suppressor protein [LiteratureReference:6791401] Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites [LiteratureReference:6791400] Structure and chromosomal assignment of the human cyclin G gene
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates CCNG1 gene expression
output	[EntityWithAccessionedSequence:R-HSA-6792489] CCNG1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6791409] TP53 binds the CCNG1 gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-6792488] Positive gene expression regulation by 'TP53 Tetramer:CCNG1 Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642814] Positive gene expression regulation by 'TP53 Tetramer:CCNG1 Gene [nucleoplasm]' Cyclin G is a transcriptional target of the p53 tumor suppressor protein
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-6792491
summation	[Summation:6792492] Upon binding to the p53 response elements in the promoter an...

Referrals

(hasEvent)	[Pathway:R-HSA-6804757] Regulation of TP53 Degradation
(precedingEvent)	[Reaction:R-HSA-6792871] CCNG1 recruits PP2A-PPP2R5C to MDM2