Reactome | TP53 binds the CCNG1 gene

Schema > Reaction > Entries

TP53 binds the CCNG1 gene Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6791407] Orlic-Milacic, Marija, 2015-08-20
dbId	6791409
displayName	TP53 binds the CCNG1 gene
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804757] Regulation of TP53 Degradation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-6792491] TP53 stimulates CCNG1 gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6791403] CCNG1 Gene [nucleoplasm] [Complex:R-HSA-3209194] TP53 Tetramer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6791406] Cyclin G is a transcriptional target of the p53 tumor suppressor protein [LiteratureReference:6791401] Identification of p53 target genes through immune selection of genomic DNA: the cyclin G gene contains two distinct p53 binding sites [LiteratureReference:6791400] Structure and chromosomal assignment of the human cyclin G gene
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 binds the CCNG1 gene
output	[Complex:R-HSA-6791405] TP53 Tetramer:CCNG1 Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6804762] TP53 forms homotetramers - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6791409
summation	[Summation:6791402] TP53 (p53) binds the p53 response element in the first intro...

Referrals

(hasEvent)	[Pathway:R-HSA-6804757] Regulation of TP53 Degradation
(precedingEvent)	[BlackBoxEvent:R-HSA-6792491] TP53 stimulates CCNG1 gene expression