Reactome | TP53 stimulates ARID3A gene expression

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TP53 stimulates ARID3A gene expression Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6791364] Orlic-Milacic, Marija, 2015-08-20
dbId	6791363
displayName	TP53 stimulates ARID3A gene expression
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6791393] ARID3A Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6791392] E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53 [LiteratureReference:6791380] Cooperation between ARID3A and p53 in the transcriptional activation of p21WAF1 in response to DNA damage [LiteratureReference:6791382] A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer [LiteratureReference:6791366] A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates ARID3A gene expression
output	[EntityWithAccessionedSequence:R-HSA-3782552] ARID3A [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6791387] TP53 binds the ARID3A gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-6791389] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:ARID3A Gene [nucleoplasm]'
regulationReference	[RegulationReference:9642831] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:ARID3A Gene [nucleoplasm]' E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-6791363
summation	[Summation:6791373] TP53 (p53) stimulates transcription of the ARID3A gene upon ...

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(hasEvent)

[Pathway:R-HSA-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest