Reactome | rRNA modification in the nucleus and cytosol

Schema > Pathway > Entries

rRNA modification in the nucleus and cytosol Show undefined attributes

authored	[InstanceEdit:6790903] May, Bruce, 2015-08-12
created	[InstanceEdit:6790904] May, Bruce, 2015-08-15
dbId	6790901
displayName	rRNA modification in the nucleus and cytosol
doi	10.3180/R-HSA-6790901.1
edited	[InstanceEdit:6790903] May, Bruce, 2015-08-12
eventOf	[Pathway:R-HSA-8868773] rRNA processing in the nucleus and cytosol - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:21688] rRNA modification
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-6790907] Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides - Homo sapiens [Reaction:R-HSA-6790905] Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA - Homo sapiens [Reaction:R-HSA-6790944] NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 - Homo sapiens [Reaction:R-HSA-6790906] EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 - Homo sapiens [Reaction:R-HSA-6790982] WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 - Homo sapiens [Reaction:R-HSA-6790994] DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 - Homo sapiens [BlackBoxEvent:R-HSA-6790987] NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 - Homo sapiens [Reaction:R-HSA-8868783] TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6792663] RNA-guided isomerization of uridine to pseudouridine--pseudouridylation [LiteratureReference:6782248] Chemistry enters nucleic acids biology: enzymatic mechanisms of RNA modification [LiteratureReference:6792652] RNA structure and function in C/D and H/ACA s(no)RNPs [LiteratureReference:6792662] Function and detection of 5-methylcytosine in eukaryotic RNA [LiteratureReference:6792643] The nucleolus: structure/function relationship in RNA metabolism [LiteratureReference:6792664] The contribution of pseudouridine to stabilities and structure of RNAs [LiteratureReference:6792660] RNA pseudouridylation: new insights into an old modification [LiteratureReference:6792651] The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification [LiteratureReference:6798636] Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications [LiteratureReference:6798702] Yeast pre-rRNA processing and modification occur cotranscriptionally [LiteratureReference:6807386] Cotranscriptional events in eukaryotic ribosome synthesis [LiteratureReference:8856923] Locations of methyl groups in 28 S rRNA of Xenopus laevis and man. Clustering in the conserved core of molecule [LiteratureReference:6790999] Eukaryotic ribosomal RNA: the recent excitement in the nucleotide modification problem [LiteratureReference:8856919] Methylated nucleotide sequences in HeLa-cell ribosomal ribonucleic acid. Correlation between the results from 'fingerprinting' hydrolysates obtained by digestion with T1 ribonuclease and with T1 plus pancreatic ribonuclease [LiteratureReference:8856926] 'View From A Bridge': A New Perspective on Eukaryotic rRNA Base Modification [LiteratureReference:8856908] The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA [LiteratureReference:8856909] Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly [LiteratureReference:6793727] Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs [LiteratureReference:8856917] The structure of the box C/D enzyme reveals regulation of RNA methylation [LiteratureReference:8856920] rRNA modifications and ribosome function
modified	[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name	rRNA modification in the nucleus and cytosol
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855036] Vincent, Nicholas G, 2016-01-30 [InstanceEdit:8856924] Sharma, Sunny, 2016-02-12
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-6790901
summation	[Summation:6798637] Human ribosomal RNAs (rRNAs) contain about 200 residues that...

Referrals

(hasEvent)

[Pathway:R-HSA-8868773] rRNA processing in the nucleus and cytosol

Cite Us!