Reactome | AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG

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AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG Show undefined attributes

authored	[InstanceEdit:5696430] Jassal, Bijay, 2015-05-29
catalystActivity	[CatalystActivity:8848570] 2-acylglycerol O-acyltransferase activity of AWAT2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:5696458] Jassal, Bijay, 2015-05-29
dbId	5696448
displayName	AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG
edited	[InstanceEdit:5696430] Jassal, Bijay, 2015-05-29
eventOf	[Pathway:R-HSA-1482883] Acyl chain remodeling of DAG and TAG - Homo sapiens
followingEvent	[Reaction:R-HSA-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 - Homo sapiens [Reaction:R-HSA-1482889] DAG is acylated to TAG by DGAT1/2 - Homo sapiens
input	[SimpleEntity:R-ALL-6782195] Acyl-CoA [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-5696449] MAG [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2465959] Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily [LiteratureReference:2466000] A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG
orthologousEvent	[Reaction:R-MMU-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Mus musculus [Reaction:R-SCE-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Saccharomyces cerevisiae [Reaction:R-SPO-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Schizosaccharomyces pombe [Reaction:R-DDI-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Dictyostelium discoideum [Reaction:R-CEL-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Caenorhabditis elegans [Reaction:R-DME-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Drosophila melanogaster [Reaction:R-GGA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Gallus gallus [Reaction:R-XTR-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Xenopus tropicalis [Reaction:R-DRE-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Danio rerio [Reaction:R-SSC-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Sus scrofa [Reaction:R-BTA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Bos taurus [Reaction:R-CFA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Canis familiaris [Reaction:R-RNO-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Rattus norvegicus
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5696448
summation	[Summation:5696450] Acyl-CoA wax alcohol acyltransferase 2 (AWAT2 aka MFAT) is a...

Referrals

(hasEvent)	[Pathway:R-HSA-1482883] Acyl chain remodeling of DAG and TAG
(precedingEvent)	[Reaction:R-HSA-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 [Reaction:R-HSA-1482889] DAG is acylated to TAG by DGAT1/2

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