Reactome | EDA:EDAR binds EDARADD

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EDA:EDAR binds EDARADD Show undefined attributes

authored	[InstanceEdit:5675651] Jassal, Bijay, 2015-02-16
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5675651] Jassal, Bijay, 2015-02-16
dbId	5675656
displayName	EDA:EDAR binds EDARADD
edited	[InstanceEdit:5675651] Jassal, Bijay, 2015-02-16
eventOf	[Pathway:R-HSA-5669034] TNFs bind their physiological receptors - Homo sapiens
input	[Complex:R-HSA-5674596] EDA:EDAR [plasma membrane] [EntityWithAccessionedSequence:R-HSA-5675659] EDARADD [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5675683] Mutations in EDARADD account for a small proportion of hypohidrotic ectodermal dysplasia cases [LiteratureReference:5675684] Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice
modified	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name	EDA:EDAR binds EDARADD
orthologousEvent	[Reaction:R-GGA-5675656] EDA:EDAR binds EDARADD - Gallus gallus [Reaction:R-SSC-5675656] EDA:EDAR binds EDARADD - Sus scrofa [Reaction:R-BTA-5675656] EDA:EDAR binds EDARADD - Bos taurus [Reaction:R-CFA-5675656] EDA:EDAR binds EDARADD - Canis familiaris [Reaction:R-RNO-5675656] EDA:EDAR binds EDARADD - Rattus norvegicus [Reaction:R-MMU-5675656] EDA:EDAR binds EDARADD - Mus musculus
output	[Complex:R-HSA-5675675] EDA:EDAR:EDARADD [plasma membrane]
releaseDate	2015-06-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5675656
summation	[Summation:5675662] Ectodysplasin-A (EDA) is a trimeric type II membrane protein...

Referrals

(hasEvent)

[Pathway:R-HSA-5669034] TNFs bind their physiological receptors