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Go!
Schema
>
Complex
>
Entries
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-HSA-9653109] p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] - Homo sapiens
consumedByEvent
[Reaction:R-HSA-9653108] Raf dimer inhibitors bind RAF heterodimers - Homo sapiens
[Reaction:R-HSA-5672969] Phosphorylation of RAF - Homo sapiens
created
[InstanceEdit:5672732] Rothfels, Karen, 2015-02-05
dbId
5672733
displayName
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane]
hasComponent
[DefinedSet:R-HSA-5672731] dephosphorylated "receiver" RAF/KSR1 [cytosol]
[Complex:R-HSA-5672729] p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
inDisease
false
includedLocation
[Compartment:70101] cytosol
inferredTo
[Complex:R-MMU-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Mus musculus
[Complex:R-RNO-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Rattus norvegicus
[Complex:R-CFA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Canis familiaris
[Complex:R-BTA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Bos taurus
[Complex:R-SSC-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Sus scrofa
[Complex:R-GGA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Gallus gallus
[Complex:R-DME-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Drosophila melanogaster
[Complex:R-CEL-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Caenorhabditis elegans
[Complex:R-PFA-5672733] p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] - Plasmodium falciparum
isChimeric
false
name
p21 RAS:GTP:homo/heterodimerized RAF complex
producedByEvent
[Reaction:R-HSA-5672966] RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers - Homo sapiens
schemaClass
Complex
species
[Species:48887] Homo sapiens
stId
R-HSA-5672733
Referrals
(normalEntity)
[EntityFunctionalStatus:6802860] gain_of_function of BRAF/RAF fusion dimers [cytosol]
[EntityFunctionalStatus:9656202] gain_of_function of p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane]
[EntityFunctionalStatus:6802894] gain_of_function of mutant RAS:inactive BRAF:RAF1 [plasma membrane]
[EntityFunctionalStatus:6802872] gain_of_function of RAS:GTP:moderate kinase activity BRAF mutants:RAF:YWHAB [plasma membrane]
[EntityFunctionalStatus:6802864] gain_of_function of RAS mutants:GTP:RAF homo/heterodimer [plasma membrane]
(input)
[Reaction:R-HSA-9653108] Raf dimer inhibitors bind RAF heterodimers
[Reaction:R-HSA-5672969] Phosphorylation of RAF
(output)
[Reaction:R-HSA-5672966] RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers
(hasComponent)
[Complex:R-HSA-9653109] p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane]
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