Reactome | EDA-3 binds EDA2R

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EDA-3 binds EDA2R Show undefined attributes

authored	[InstanceEdit:5669069] Jassal, Bijay, 2015-01-30
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5669069] Jassal, Bijay, 2015-01-30
dbId	5669013
displayName	EDA-3 binds EDA2R
edited	[InstanceEdit:5669069] Jassal, Bijay, 2015-01-30
eventOf	[Pathway:R-HSA-5669034] TNFs bind their physiological receptors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-5669079] EDA-3 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-5669018] EDA2R [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5674587] Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells [LiteratureReference:5674589] The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity
modified	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name	EDA-3 binds EDA2R
orthologousEvent	[Reaction:R-GGA-5669013] EDA-3 binds EDA2R - Gallus gallus [Reaction:R-XTR-5669013] EDA-3 binds EDA2R - Xenopus tropicalis [Reaction:R-DRE-5669013] EDA-3 binds EDA2R - Danio rerio [Reaction:R-RNO-5669013] EDA-3 binds EDA2R - Rattus norvegicus [Reaction:R-MMU-5669013] EDA-3 binds EDA2R - Mus musculus
output	[Complex:R-HSA-5674595] EDA-3:EDA2R [plasma membrane]
releaseDate	2015-06-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5692509] Ware, Carl F, Virgen-Slane, Richard, Rajput, Akhil, 2015-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5669013
summation	[Summation:5674591] Ectodysplasin-A (EDA) is a trimeric type II membrane protein...

Referrals

(hasEvent)

[Pathway:R-HSA-5669034] TNFs bind their physiological receptors