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Schema
>
BlackBoxEvent
>
Entries
Hh C-terminal fragments are degraded by the proteasome
Show undefined attributes
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authored
[InstanceEdit:5358461] Rothfels, Karen, 2014-03-28
catalystActivity
[CatalystActivity:68824] endopeptidase activity of 26S proteasome [cytosol]
category
omitted
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:5362449] Rothfels, Karen, 2014-04-15
dbId
5362448
displayName
Hh C-terminal fragments are degraded by the proteasome
edited
[InstanceEdit:5364056] D'Eustachio, Peter, 2014-04-19
eventOf
[Pathway:R-HSA-5358346] Hedgehog ligand biogenesis - Homo sapiens
input
[CandidateSet:R-HSA-5362391] ub C-terminal Hh fragments [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:5358239] Processing and turnover of the Hedgehog protein in the endoplasmic reticulum
[LiteratureReference:5359146] Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum
modified
[InstanceEdit:10655440] Wright, Adam, 2024-03-08
name
Hh C-terminal fragments are degraded by the proteasome
orthologousEvent
[BlackBoxEvent:R-DME-5362448] Hh C-terminal fragments are degraded by the proteasome - Drosophila melanogaster
[BlackBoxEvent:R-DRE-5362448] Hh C-terminal fragments are degraded by the proteasome - Danio rerio
[BlackBoxEvent:R-SSC-5362448] Hh C-terminal fragments are degraded by the proteasome - Sus scrofa
[BlackBoxEvent:R-BTA-5362448] Hh C-terminal fragments are degraded by the proteasome - Bos taurus
[BlackBoxEvent:R-CFA-5362448] Hh C-terminal fragments are degraded by the proteasome - Canis familiaris
[BlackBoxEvent:R-RNO-5362448] Hh C-terminal fragments are degraded by the proteasome - Rattus norvegicus
[BlackBoxEvent:R-MMU-5362448] Hh C-terminal fragments are degraded by the proteasome - Mus musculus
output
[DefinedSet:R-HSA-113595] Ub [cytosol]
precedingEvent
[Reaction:R-HSA-5362459] VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol - Homo sapiens
releaseDate
2014-06-10
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5483156] Liu, Yulu Cherry, 2014-05-16
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-5362448
summation
[Summation:5362435] After retrotranslocation to the cytosol, Hh-C is degraded by...
Referrals
(hasEvent)
[Pathway:R-HSA-5358346] Hedgehog ligand biogenesis
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