Reactome | acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]

Schema > Reaction > Entries

acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] Show undefined attributes

authored	[InstanceEdit:449910] D'Eustachio, P, 2009-12-09
catalystActivity	[CatalystActivity:449908] acetate-CoA ligase activity of ACSS1 [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9643691] acetate-CoA ligase activity of ACSS1 [mitochondrial matrix] Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:449907] D'Eustachio, P, 2009-12-09
crossReference	[DatabaseIdentifier:11881048] Rhea:23177
dbId	449911
displayName	acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]
edited	[InstanceEdit:517475] D'Eustachio, P, 2010-02-18
eventOf	[Pathway:R-HSA-71384] Ethanol oxidation - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-113539] CH3COO- [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:449916] Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]
orthologousEvent	[Reaction:R-PFA-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Plasmodium falciparum [Reaction:R-SCE-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Saccharomyces cerevisiae [Reaction:R-SPO-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Schizosaccharomyces pombe [Reaction:R-DDI-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Dictyostelium discoideum [Reaction:R-GGA-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Gallus gallus [Reaction:R-XTR-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Xenopus tropicalis [Reaction:R-SSC-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Sus scrofa [Reaction:R-BTA-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Bos taurus [Reaction:R-CFA-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Canis familiaris [Reaction:R-RNO-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Rattus norvegicus [Reaction:R-MMU-449911] acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] - Mus musculus
output	[SimpleEntity:R-ALL-113559] Ac-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-71723] acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] - Homo sapiens
releaseDate	2010-03-16
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:532425] Jassal, Bijay, 2010-02-26
revised	[InstanceEdit:449910] D'Eustachio, P, 2009-12-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-449911
summation	[Summation:449915] ACSS1 (acyl-CoA synthetase short-chain family member 1) in t...

Referrals

(hasEvent)

[Pathway:R-HSA-71384] Ethanol oxidation