Reactome | Transport of inorganic cations/anions and amino acids/oligopeptides

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Transport of inorganic cations/anions and amino acids/oligopeptides Show undefined attributes

authored	[InstanceEdit:425388] Jassal, Bijay, 2009-06-04
created	[InstanceEdit:425388] Jassal, Bijay, 2009-06-04
dbId	425393
displayName	Transport of inorganic cations/anions and amino acids/oligopeptides
edited	[InstanceEdit:425388] Jassal, Bijay, 2009-06-04
eventOf	[Pathway:R-HSA-425407] SLC-mediated transmembrane transport - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:18821] ion transport
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-425381] Bicarbonate transporters - Homo sapiens [Pathway:R-HSA-425561] Sodium/Calcium exchangers - Homo sapiens [Pathway:R-HSA-425986] Sodium/Proton exchangers - Homo sapiens [Pathway:R-HSA-426117] Cation-coupled Chloride cotransporters - Homo sapiens [Pathway:R-HSA-427601] Multifunctional anion exchangers - Homo sapiens [Pathway:R-HSA-427652] Sodium-coupled phosphate cotransporters - Homo sapiens [Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens [Reaction:R-HSA-428015] SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol - Homo sapiens [Pathway:R-HSA-428643] Organic anion transporters - Homo sapiens [Pathway:R-HSA-428559] Proton-coupled neutral amino acid transporters - Homo sapiens [Pathway:R-HSA-427975] Proton/oligopeptide cotransporters - Homo sapiens [Reaction:R-HSA-428625] Vesicular inhibitory amino acid transport - Homo sapiens [Reaction:R-HSA-5340130] CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol - Homo sapiens [Reaction:R-HSA-8855062] SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:427985] Analysis and update of the human solute carrier (SLC) gene superfamily [LiteratureReference:433145] SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models [LiteratureReference:425575] The sodium/calcium exchanger family-SLC8 [LiteratureReference:426016] Diversity of the mammalian sodium/proton exchanger SLC9 gene family [LiteratureReference:426105] Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family [LiteratureReference:427623] The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors [LiteratureReference:433775] Renal physiology of SLC26 anion exchangers [LiteratureReference:427577] The solute carrier 26 family of proteins in epithelial ion transport [LiteratureReference:433772] Cochlear outer hair cell motility [LiteratureReference:433767] Na+/Ca2+-K+ exchangers (NCKX): functional properties and physiological roles [LiteratureReference:433768] Proximal tubular handling of phosphate: A molecular perspective [LiteratureReference:427636] Phosphate transporters: a tale of two solute carrier families
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	Transport of inorganic cations/anions and amino acids/oligopeptides
orthologousEvent	[Pathway:R-BTA-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Bos taurus [Pathway:R-RNO-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Rattus norvegicus [Pathway:R-SSC-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Sus scrofa [Pathway:R-DRE-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Danio rerio [Pathway:R-XTR-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Xenopus tropicalis [Pathway:R-GGA-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Gallus gallus [Pathway:R-DME-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Drosophila melanogaster [Pathway:R-CEL-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Caenorhabditis elegans [Pathway:R-DDI-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Dictyostelium discoideum [Pathway:R-SPO-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Schizosaccharomyces pombe [Pathway:R-SCE-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Saccharomyces cerevisiae [Pathway:R-PFA-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Plasmodium falciparum [Pathway:R-CFA-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Canis familiaris [Pathway:R-MMU-425393] Transport of inorganic cations/anions and amino acids/oligopeptides - Mus musculus
releaseDate	2009-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-425393
summation	[Summation:433144] Teleologically, one might argue that inorganic cation and an...

Referrals

(hasEvent)	[Pathway:R-HSA-425407] SLC-mediated transmembrane transport
(hasEncapsulatedEvent)	[Pathway:R-HSA-71403] Citric acid cycle (TCA cycle) [Pathway:R-HSA-70326] Glucose metabolism [Pathway:R-HSA-75105] Fatty acyl-CoA biosynthesis
(normalPathway)	[Pathway:R-HSA-5619113] Defective SLC3A1 causes cystinuria (CSNU) [Pathway:R-HSA-5619104] Defective SLC12A1 causes Bartter syndrome 1 (BS1) [Pathway:R-HSA-5619111] Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) [Pathway:R-HSA-5660862] Defective SLC7A7 causes lysinuric protein intolerance (LPI) [Pathway:R-HSA-5619087] Defective SLC12A3 causes Gitelman syndrome (GS) [Pathway:R-HSA-5660686] Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) [Pathway:R-HSA-5619085] Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1) [Pathway:R-HSA-5619076] Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) [Pathway:R-HSA-5619096] Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) [Pathway:R-HSA-5619097] Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) [Pathway:R-HSA-5619094] Variant SLC6A14 may confer susceptibility towards obesity [Pathway:R-HSA-5619092] Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) [Pathway:R-HSA-5619054] Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) [Pathway:R-HSA-5619055] Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) [Pathway:R-HSA-5619052] Defective SLC9A9 causes autism 16 (AUTS16) [Pathway:R-HSA-5619040] Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) [Pathway:R-HSA-5619041] Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG) [Pathway:R-HSA-5619046] Defective SLC26A4 causes Pendred syndrome (PDS) [Pathway:R-HSA-5619045] Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) [Pathway:R-HSA-5619067] Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) [Pathway:R-HSA-5619062] Defective SLC1A3 causes episodic ataxia 6 (EA6) [Pathway:R-HSA-5619039] Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) [Pathway:R-HSA-5619036] Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) [Pathway:R-HSA-5659729] Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria [Pathway:R-HSA-5660883] Defective SLC7A9 causes cystinuria (CSNU) [Pathway:R-HSA-5659735] Defective SLC6A19 causes Hartnup disorder (HND)

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