Reactome | glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate

Schema > Reaction > Entries

authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
catalystActivity	[CatalystActivity:379594] glycine-tRNA ligase activity of GARS dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:379999] D'Eustachio, P, 2008-11-06 23:24:17
dbId	380048
displayName	glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
eventOf	[Pathway:R-HSA-379716] Cytosolic tRNA aminoacylation - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29424] Gly [cytosol] [GenomeEncodedEntity:R-HSA-379766] tRNA(Gly) [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:389207] Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [GenomeEncodedEntity:R-HSA-379784] Gly-tRNA(Gly) [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
revised	[InstanceEdit:389225] D'Eustachio, P, 2008-12-23 21:40:28
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-380048
summation	[Summation:379985] GARS (cytosolic glycyl tRNA synthetase) catalyzes the reacti...

(hasEvent)

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