Reactome | Receptor CCR10 binds CCL27 and 28 ligands

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Receptor CCR10 binds CCL27 and 28 ligands Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:373072] Jassal, Bijay, 2008-07-14
dbId	373086
displayName	Receptor CCR10 binds CCL27 and 28 ligands
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-380108] Chemokine receptors bind chemokines - Homo sapiens
followingEvent	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[DefinedSet:R-HSA-373322] CCL27,28 [extracellular region] [EntityWithAccessionedSequence:R-HSA-373126] CCR10 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:373255] Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2) [LiteratureReference:373271] Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC) [LiteratureReference:373290] Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine
modified	[InstanceEdit:10427439] Wright, Adam, 2024-03-07
name	Receptor CCR10 binds CCL27 and 28 ligands
orthologousEvent	[Reaction:R-DRE-373086] Receptor CCR10 binds CCL27 and 28 ligands - Danio rerio [Reaction:R-SSC-373086] Receptor CCR10 binds CCL27 and 28 ligands - Sus scrofa [Reaction:R-BTA-373086] Receptor CCR10 binds CCL27 and 28 ligands - Bos taurus [Reaction:R-CFA-373086] Receptor CCR10 binds CCL27 and 28 ligands - Canis familiaris [Reaction:R-RNO-373086] Receptor CCR10 binds CCL27 and 28 ligands - Rattus norvegicus [Reaction:R-MMU-373086] Receptor CCR10 binds CCL27 and 28 ligands - Mus musculus
output	[Complex:R-HSA-373236] CCR10:CCL27,28 [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-373086
summation	[Summation:373315] CCR10 (previously known as GPR2) (Jarmin DI et al, 2000) is ...

Referrals

(hasEvent)	[Pathway:R-HSA-380108] Chemokine receptors bind chemokines
(precedingEvent)	[Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi