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Entries
SLC25A10 mediates exchange of malate and phosphate
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authored
[InstanceEdit:377490] D'Eustachio, P, 2008-09-12 21:47:19
catalystActivity
[CatalystActivity:372844] dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane]
catalystActivityReference
[CatalystActivityReference:9815326] dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane] SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency
category
transition
compartment
[Compartment:70101] cytosol
[Compartment:70616] mitochondrial inner membrane
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:372841] D'Eustachio, P, 2008-07-07 20:55:00
crossReference
[DatabaseIdentifier:11880038] Rhea:71607
dbId
372843
displayName
SLC25A10 mediates exchange of malate and phosphate
edited
[InstanceEdit:377490] D'Eustachio, P, 2008-09-12 21:47:19
eventOf
[Pathway:R-HSA-428643] Organic anion transporters - Homo sapiens
followingEvent
[Reaction:R-HSA-9012036] ME1 tetramer decarboxylates MAL to PYR - Homo sapiens
input
[SimpleEntity:R-ALL-113544] MAL [mitochondrial matrix]
[SimpleEntity:R-ALL-29372] Pi [cytosol]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:372842] Organization and sequence of the gene for the human mitochondrial dicarboxylate carrier: evolution of the carrier family
[LiteratureReference:9815327] SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency
modified
[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
SLC25A10 mediates exchange of malate and phosphate
(S)-malate(in) + phosphate(out) => (S)-malate(out) + phosphate(in)
orthologousEvent
[Reaction:R-GGA-372852] malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] - Gallus gallus
[Reaction:R-SCE-372843] SLC25A10 mediates exchange of malate and phosphate - Saccharomyces cerevisiae
[Reaction:R-DDI-372843] SLC25A10 mediates exchange of malate and phosphate - Dictyostelium discoideum
[Reaction:R-CEL-372843] SLC25A10 mediates exchange of malate and phosphate - Caenorhabditis elegans
[Reaction:R-DME-372843] SLC25A10 mediates exchange of malate and phosphate - Drosophila melanogaster
[Reaction:R-GGA-372843] SLC25A10 mediates exchange of malate and phosphate - Gallus gallus
[Reaction:R-DRE-372843] SLC25A10 mediates exchange of malate and phosphate - Danio rerio
[Reaction:R-SSC-372843] SLC25A10 mediates exchange of malate and phosphate - Sus scrofa
[Reaction:R-BTA-372843] SLC25A10 mediates exchange of malate and phosphate - Bos taurus
[Reaction:R-CFA-372843] SLC25A10 mediates exchange of malate and phosphate - Canis familiaris
[Reaction:R-RNO-372843] SLC25A10 mediates exchange of malate and phosphate - Rattus norvegicus
[Reaction:R-MMU-372843] SLC25A10 mediates exchange of malate and phosphate - Mus musculus
output
[SimpleEntity:R-ALL-198498] MAL [cytosol]
[SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
precedingEvent
[Reaction:R-HSA-70982] FH tetramer hydrates fumarate to L-malate - Homo sapiens
releaseDate
2008-09-30
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12
[InstanceEdit:9815859] Hill, David P, 2022-08-29
revised
[InstanceEdit:9815860] D'Eustachio, Peter, 2022-08-29
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-372843
summation
[Summation:372846] SLC25A10, the mitochondrial dicarboxylate carrier protein in...
Referrals
(hasEvent)
[Pathway:R-HSA-428643] Organic anion transporters
(precedingEvent)
[Reaction:R-HSA-9012036] ME1 tetramer decarboxylates MAL to PYR
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