Reactome | E2F1, E2F2, or E2F3 and SP1 bind p14ARF promoter

Schema > Reaction > Entries

E2F1, E2F2, or E2F3 and SP1 bind p14ARF promoter Show undefined attributes

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3209104] Orlic-Milacic, M, 2013-03-01
dbId	3209096
displayName	E2F1, E2F2, or E2F3 and SP1 bind p14ARF promoter
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
eventOf	[Pathway:R-HSA-2559585] Oncogene Induced Senescence - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-3209109] E2F1/E2F2/E2F3 and SP1 stimulate transcription of p14ARF mRNA - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-3200017] CDKN2A gene [nucleoplasm] [Complex:R-HSA-1227905] E2F1,E2F2,E2F3:TFDP1,TFDP2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-1592223] SP1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3209099] Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E2F1, E2F2, or E2F3 and SP1 bind p14ARF promoter
output	[Complex:R-HSA-3209097] DP1/2: E2F1/2/3: SP1: CDKN2A Gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes - Homo sapiens
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3209096
summation	[Summation:3245947] E2F1, E2F2 or E2F3 forms a complex with the transcription fa...

Referrals

(hasEvent)	[Pathway:R-HSA-2559585] Oncogene Induced Senescence
(precedingEvent)	[BlackBoxEvent:R-HSA-3209109] E2F1/E2F2/E2F3 and SP1 stimulate transcription of p14ARF mRNA

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